RBC

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HTLV I/II and HTLV III seroprevalence in blood product recipients

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Abstract

Human T-cell leukemia virus type I (HTLV-I) has been strongly implicated as the etiology of adult T-cell leukemia (ATL), a T-cell type non-Hodgkin’s lymphoma with leukemic manifestations in Japan, the Caribbean, and the southeastern United States. The prevalence of serum antibody specific for one core antigen of HTLV-I, p24, has been found to be high in patients with ATL, and higher in relatives of these patients than in general population controls.… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Human T-cell leukemia virus (HTLV-I) p24 antibody in New York City blood product recipients

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Abstract

Human T-cell leukemia virus (HTLV-I)

is known to be associated with certain hematologic malignancies, and a related virus, HTLV-III/LAV, might be the cause of AIDS. Some persons with AIDS have had evidence of HTLV-I infection. Unrelated to these findings, it has been suggested that HTLV-I is transmitted via blood products.… Read more

Illustration(s) pertain to the topic addressed in this publication, not the specific research or data presented in the publication

Immune status of blood product recipients

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Abstract

Persons with hemophilia are at risk of the acquired immunodeficiency syndrome (AIDS), and clinically asymptomatic hemophiliacs have shown a high incidence of AIDS-like immune abnormalities, facts leading to speculation that many hemophiliacs have been exposed to the AIDS agent through their blood products.… Read more